1. Product description
Hyaluronic acid (referred to as HA), also known as hyaluronic acid in the market, the molecular formula is (C14H21NO11)n, pH is 3.0-5.0, it is composed of N-acetylglucosamine and D-glucuronic acid disaccharide units are repeatedly connected. The macromolecular mucopolysaccharide, HA has super water absorption capacity, can absorb 1000 times its own weight of water, is an ideal natural moisturizing factor, so it is widely used in cosmetics.
Sodium Hyaluronate , also known as sodium hyaluronate on the market, has a chemical formula of (C14H20NO11Na)n and a pH of 5.0-8.5. It is the sodium salt form of hyaluronic acid.
Both "hyaluronic acid" or "sodium hyaluronate" can play a role in moisturizing and locking water, and "hyaluronic acid" or "sodium hyaluronate" with the same molecular weight have similar effects.
2. Molecular weight segment and corresponding efficacy：
High molecular weight sodium hyaluronate（＞1.5MDa）
Efficacy: Polymer HA has good viscoelasticity and moisturizing properties, and can form a breathable film on the skin surface to prevent moisture loss and protect the skin.
Sodium hyaluronate（1.0MDa-1.5MDa）
Efficacy: After being absorbed by the skin, sodium hyaluronate quickly replenishes the moisture of each layer of cells, activates cell function, accelerates the renewal and iteration of the skin, and keeps moisturizing for a long time.
Low molecular weight sodium hyaluronate （＜1.0MDa）
Efficacy: soften the stratum corneum, open the absorption channel of the skin, restore the vitality of collagen and elastin, and make the skin smooth and elastic.
Hyaluronic acid（＜50KDa）
Efficacy: soften the stratum corneum, speed up skin metabolism; inhibit oil secretion.
Hydrolyzed Hyaluronic Acid（30KDa-50KDa）
Efficacy: Transdermal absorption plays a role, deeply nourishes the skin, improves skin elasticity and reduces wrinkles.
Oligo sodium hyaluronate（＜10K Da）
Efficacy: directly to the bottom of the skin, deep moisturizing, anti-oxidation and anti-aging.
3.Product list：
| Raw material trade name | INCI name | pH | Molecular Weigh（Da） |
| moistuHA® High molecular weight sodium hyaluronate | SODIUM HYALURONATE | 5.0～8.5 | ＞1.5M |
| moistuHA® sodium hyaluronate | SODIUM HYALURONATE | 5.0～8.5 | 1.0M～1.5M |
| moistuHA® Low molecular weight sodium hyaluronate | SODIUM HYALURONATE | 5.0～8.5 | ＜1.0M |
| moistuHA® Low molecular weight sodium hyaluronate (FST-20-40) | SODIUM HYALURONATE | 5.0～8.5 | 200K～400K |
| moistuHA® hyaluronic acid | HYALURONIC ACID | 3.0～5.0 | ＜50K |
| moistuHA® Hydrolyzed Hyaluronic Acid | HYDROLYZED HYALURONIC ACID | 3.0～5.0 | 30K～50K |
| moistuHA® Oligo sodium hyaluronate | HYDROLYZED SODIUM HYALURONATE | 5.0～8.5 | ＜10K |
4. Product inspection standard：
| Test Items | Appearance | Reaction of sodium | Infrared absorption | Sodium hyaluronate content | Glucuronic acid content | Transparency |
| Specification | White or almost white powder or grain | Positive | Complied with the reference spectrum of sodium hyaluronate | ≥93% | ≥45% | ≥99% |
| Test Items | pH | Heavy metal | protein | Intrinsic viscosity, dl/g | Average molecular weight, Da | Loss on drying |
| Specification | 5.0-8.5 | ≤20ppm | ≤0.05% | Measured Value | Measured Value | ≤10% |
| Test Items | Ignition residue | Bacteria counts | Mold & Yeast | staphylococcus aureus/g | pseudomonas aeruginosa/g | |
| Specification | ≤20% | ≤100CFU/g | ≤10CFU/g | Negative | Negative |
5. Product application scope：
Skin care products: toner, spray, lotion, essence, cream, lip balm, etc.
Cleaning products: facial cleanser, shower gel, shampoo, conditioner, etc.
Care products: facial mask, body lotion, foot mask, hand mask, etc.
6. Proposed dosage：0.1%-0.5%